First-in-Human Clinical Trials

Our researchers and medical doctors are collaborating with scientists and physicians all over the world who are working to find better treatment options, and ultimately a cure, for brain cancer. Some of the most exciting trials are being hosted right here at the Preston A. Wells Jr. Center for Brain Tumor Therapy, including several trials that are being implemented for people for the first time. Some of the most unique trials in the world are being led by researchers and doctors here on our campus.


Pediatrics

ACTION: Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas
CONTACT:
Marcia Hodik, RN, BSHS
Phone: 352.273.6971
Email: marcia.hodik@neurosurgery.ufl.edu


Adults

IMPACT: Phase I Study —To Assess Safety and Feasibility of IL-8 Receptor Modified Patient-derived Activated CD70 CAR T cell Therapy in CD70+ and MGMT-unmethylated Adult GBM
CONTACT:
Phuong Deleyrolle, RN
Phone: 352.273.5529
Email: phuong.deleyrolle@neurosurgery.ufl.edu

PNOC 020: A Phase I/II Study of RNA-lipid particle (RNA-LP) vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

CONTACT:
Marcia Hodik, RN, BSHS
Phone: 352.273.6971
Email: marcia.hodik@neurosurgery.ufl.edu